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T-cell epitope conservation across allergen species is a major determinant of immunogenicity
BACKGROUND: Patients with pollen allergies are frequently poly-sensitized. Pollen contain epitopes that are conserved across multiple species. OBJECTIVE: Demostrate that cross-reactive T-cells which recognize conserved epitopes show higher levels of expansion than T-cells recognizing monospecific ep...
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| Udgivet i: | J Allergy Clin Immunol |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975972/ https://ncbi.nlm.nih.gov/pubmed/26883464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.11.034 |
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