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Cholesterol-Dependent Phase-Demixing in Lipid Bilayers as a Switch for the Activity of the Phosphoinositide-Binding Cytoskeletal Protein Gelsolin
The lateral distribution of phosphatidylinositol 4,5-bisphosphate (PIP(2)) in lipid bilayers is affected both by divalent cation-mediated attractions and cholesterol-dependent phase demixing. The effects of lateral redistribution of PIP(2) within a membrane on PIP(2)–protein interactions are explore...
Gardado en:
| Publicado en: | Biochemistry |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975948/ https://ncbi.nlm.nih.gov/pubmed/27224309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01363 |
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