Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus

BACKGROUND: Oncolytic viral efficacy may be limited by the penetration of the virus into tumors. This may be enhanced by intraoperative application of virus immediately after surgical resection. METHODS: Oncolytic vaccinia virus GLV-1h68 was delivered in silk-elastin-like protein polymer (SELP) in v...

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Udgivet i:Head Neck
Main Authors: Price, Daniel L., Li, Pingdong, Chen, Chun-Hao, Wong, Danni, Yu, Zhenkun, Chen, Nanhai G., Yu, Yong A., Szalay, Aladar A., Cappello, Joseph, Fong, Yuman, Wong, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975925/
https://ncbi.nlm.nih.gov/pubmed/25244076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.23877
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