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W44X mutation in the WWOX gene causes intractable seizures and developmental delay: a case report
BACKGROUND: WW domain containing oxidoreductase (WWOX) gene was cloned in 2000; alteration has been seen in many cancer cells. It acts as a tumor suppresser by blocking cell growth and causing apoptosis. WWOX protein showed different expression of mice brain and spinal cord, for which deletion cause...
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| Publicado no: | BMC Med Genet |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975905/ https://ncbi.nlm.nih.gov/pubmed/27495153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-016-0317-z |
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