Subclass analysis of donor HLA‐specific IgG in antibody‐incompatible renal transplantation reveals a significant association of IgG(4) with rejection and graft failure

Donor HLA‐specific antibodies (DSAs) can cause rejection and graft loss after renal transplantation, but their levels measured by the current assays are not fully predictive of outcomes. We investigated whether IgG subclasses of DSA were associated with early rejection and graft failure. DSA levels...

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Detalhes bibliográficos
Publicado no:Transpl Int
Main Authors: Khovanova, Natasha, Daga, Sunil, Shaikhina, Torgyn, Krishnan, Nithya, Jones, James, Zehnder, Daniel, Mitchell, Daniel, Higgins, Robert, Briggs, David, Lowe, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975692/
https://ncbi.nlm.nih.gov/pubmed/26264744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/tri.12648
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