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Mechanisms of Xenobiotic Receptor Activation: Direct vs. Indirect

The so-called xenobiotic receptors (XRs) have functionally evolved into cellular sensors for both endogenous and exogenous stimuli by regulating the transcription of genes encoding drug-metabolizing enzymes and transporters, as well as those involving energy homeostasis, cell proliferation, and/or i...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Mackowiak, Bryan, Wang, Hongbing
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975672/
https://ncbi.nlm.nih.gov/pubmed/26877237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.02.006
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