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Mechanisms of Xenobiotic Receptor Activation: Direct vs. Indirect
The so-called xenobiotic receptors (XRs) have functionally evolved into cellular sensors for both endogenous and exogenous stimuli by regulating the transcription of genes encoding drug-metabolizing enzymes and transporters, as well as those involving energy homeostasis, cell proliferation, and/or i...
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Published in: | Biochim Biophys Acta |
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Main Authors: | , |
Format: | Artigo |
Language: | Inglês |
Published: |
2016
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975672/ https://ncbi.nlm.nih.gov/pubmed/26877237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2016.02.006 |
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