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Phosphorylation of Cysteine String Protein Triggers a Major Conformational Switch
Cysteine string protein (CSP) is a member of the DnaJ/Hsp40 chaperone family that localizes to neuronal synaptic vesicles. Impaired CSP function leads to neurodegeneration in humans and model organisms as a result of misfolding of client proteins involved in neurotransmission. Mammalian CSP is phosp...
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| 出版年: | Structure |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cell Press
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975591/ https://ncbi.nlm.nih.gov/pubmed/27452402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.06.009 |
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