The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin, Hippo, and Warts

Hippo signaling acts as a master regulatory pathway controlling growth, proliferation, and apoptosis and also ensures that variations in proliferation do not alter organ size. How the pathway coordinates restricting proliferation with organ size control remains a major unanswered question. Here we i...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Jahanshahi, Maryam, Hsiao, Kuangfu, Jenny, Andreas, Pfleger, Cathie M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975479/
https://ncbi.nlm.nih.gov/pubmed/27494403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006198
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