Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.

Binding of interleukin 2 (IL-2) to its receptor generates intracellular signals, including the activation of tyrosine and serine/threonine kinases. In this study the activation of the serine/threonine-specific ribosomal protein S6 kinases in response to IL-2 was analyzed in the murine T-cell line CT...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Calvo, V, Crews, C M, Vik, T A, Bierer, B E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1380162/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7571
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