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Pharmacokinetics and Pharmacodynamics of Extended Infusion Versus Short Infusion Piperacillin-Tazobactam in Critically Ill Patients Undergoing CRRT

BACKGROUND AND OBJECTIVES: Infection is the most common cause of death in severe AKI, but many patients receiving continuous RRT do not reach target antibiotic concentrations in plasma. Extended infusion of β-lactams is associated with improved target attainment in critically ill patients; thus, we...

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Vydáno v:Clin J Am Soc Nephrol
Hlavní autoři: Shotwell, Matthew S., Nesbitt, Ross, Madonia, Phillip N., Gould, Edward R., Connor, Michael J., Salem, Charbel, Aduroja, Olufemi A., Amde, Milen, Groszek, Joseph J., Wei, Peilin, Taylor, Maria E., Tolwani, Ashita J., Fissell, William H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974884/
https://ncbi.nlm.nih.gov/pubmed/27197907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.10260915
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