Rationale and design of the multicenter randomized trial investigating the effects of levosimendan pretreatment in patients with low ejection fraction (≤40 %) undergoing CABG with cardiopulmonary bypass (LICORN study)

BACKGROUND: Patients with a left ventricular ejection fraction (LVEF) of less than 40 % are at high risk of developing postoperative low cardiac output syndrome (LCOS). Despite actual treatments (inotropic agents and/or mechanical assist devices), the mortality rate of such patients remains very hig...

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Detalhes bibliográficos
Publicado no:J Cardiothorac Surg
Main Authors: Caruba, Thibaut, Hourton, Delphine, Sabatier, Brigitte, Rousseau, Dominique, Tibi, Annick, Hoffart-Jourdain, Cécile, Souag, Akim, Freitas, Nelly, Yjjou, Mounia, Almeida, Carla, Gomes, Nathalie, Aucouturier, Pascaline, Djadi-Prat, Juliette, Menasché, Philippe, Chatellier, Gilles, Cholley, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974786/
https://ncbi.nlm.nih.gov/pubmed/27496105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13019-016-0530-z
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