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Whole genome sequencing reveals mycobacterial microevolution among concurrent isolates from sputum and blood in HIV infected TB patients

BACKGROUND: In the context of advanced immunosuppression, M. tuberculosis is known to cause detectable mycobacteremia. However, little is known about the intra-patient mycobacterial microevolution and the direction of seeding between the sputum and blood compartments. METHODS: From a diagnostic stud...

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Detalhes bibliográficos
Publicado no:BMC Infect Dis
Main Authors: Ssengooba, Willy, de Jong, Bouke C., Joloba, Moses L., Cobelens, Frank G., Meehan, Conor J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974755/
https://ncbi.nlm.nih.gov/pubmed/27495002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1737-2
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