Hydroxylation of diverse flavonoids by CYP450 BM3 variants: biosynthesis of eriodictyol from naringenin in whole cells and its biological activities

BACKGROUND: Cytochrome P450 monooxygenase constitutes a significant group of oxidative enzymes that can introduce an oxygen atom in a high regio- and stereo-selectivity mode. We used the Bacillus megaterium cytochrome P450 BM3 (CYP450 BM3) and its variants namely mutant 13 (M13) and mutant 15 (M15)...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Chu, Luan Luong, Pandey, Ramesh Prasad, Jung, Narae, Jung, Hye Jin, Kim, Eun-Hee, Sohng, Jae Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974697/
https://ncbi.nlm.nih.gov/pubmed/27495155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0533-4
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