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Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase.

Ciprofibrate, a hypolipidemic drug that acts as a peroxisome proliferator, induces the transcription of genes encoding peroxisomal beta-oxidation enzymes. To identify cis-acting promoter elements involved in this induction, 5.8 kilobase pairs of promoter sequence from the gene encoding rat peroxisom...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Zhang, B, Marcus, S L, Sajjadi, F G, Alvares, K, Reddy, J K, Subramani, S, Rachubinski, R A, Capone, J P
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7541
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