Genetic Polymorphisms Associated to Folate Transport as Predictors of Increased Risk for Acute Lymphoblastic Leukemia in Mexican Children

Acute lymphoblastic leukemia (ALL) is a frequent neoplasia occurring in children. The most commonly used drug for the treatment of ALL is methotrexate (MTX), an anti-folate agent. Previous studies suggest that folate transporters play a role in ALL prognosis and that genetic polymorphism of genes en...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zaruma-Torres, Fausto, Lares-Asseff, Ismael, Lima, Aurea, Reyes-Espinoza, Aarón, Loera-Castañeda, Verónica, Sosa-Macías, Martha, Galaviz-Hernández, Carlos, Arias-Peláez, María C., Reyes-López, Miguel A., Quiñones, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974492/
https://ncbi.nlm.nih.gov/pubmed/27547186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00238
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