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Mucosal Langerhans Cells Promote Differentiation of Th17 Cells in a Murine Model of Periodontitis but Are Not Required for Porphyromonas gingivalis–Driven Alveolar Bone Destruction

Periodontitis is a chronic oral inflammatory disease affecting one in five individuals that can lead to tooth loss. CD4(+) Th cells activated by a microbial biofilm are thought to contribute to the destruction of alveolar bone surrounding teeth by influencing osteoclastogenesis through IL-17A and re...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Bittner-Eddy, Peter D., Fischer, Lori A., Kaplan, Daniel H., Thieu, Kathleen, Costalonga, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974489/
https://ncbi.nlm.nih.gov/pubmed/27402698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502693
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