The Yeast Mitochondrial RNA Polymerase and Transcription Factor Complex Catalyzes Efficient Priming of DNA Synthesis on Single-stranded DNA

Primases use single-stranded (ss) DNAs as templates to synthesize short oligoribonucleotide primers that initiate lagging strand DNA synthesis or reprime DNA synthesis after replication fork collapse, but the origin of this activity in the mitochondria remains unclear. Herein, we show that the Sacch...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Ramachandran, Aparna, Nandakumar, Divya, Deshpande, Aishwarya P., Lucas, Thomas P., R-Bhojappa, Ramanagouda, Tang, Guo-Qing, Raney, Kevin, Yin, Y. Whitney, Patel, Smita S.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974394/
https://ncbi.nlm.nih.gov/pubmed/27311715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740282
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