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The Yeast Mitochondrial RNA Polymerase and Transcription Factor Complex Catalyzes Efficient Priming of DNA Synthesis on Single-stranded DNA

Primases use single-stranded (ss) DNAs as templates to synthesize short oligoribonucleotide primers that initiate lagging strand DNA synthesis or reprime DNA synthesis after replication fork collapse, but the origin of this activity in the mitochondria remains unclear. Herein, we show that the Sacch...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Ramachandran, Aparna, Nandakumar, Divya, Deshpande, Aishwarya P., Lucas, Thomas P., R-Bhojappa, Ramanagouda, Tang, Guo-Qing, Raney, Kevin, Yin, Y. Whitney, Patel, Smita S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974394/
https://ncbi.nlm.nih.gov/pubmed/27311715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740282
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