Creatine target engagement with brain bioenergetics: a dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression

Major depressive disorder (MDD) often begins during adolescence and is projected to become the leading cause of global disease burden by the year 2030. Yet, approximately 40 % of depressed adolescents fail to respond to standard antidepressant treatment with a selective serotonin reuptake inhibitor...

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Veröffentlicht in:Amino Acids
Hauptverfasser: Kondo, Douglas G., Forrest, Lauren N., Shi, Xianfeng, Sung, Young-Hoon, Hellem, Tracy L., Huber, Rebekah S., Renshaw, Perry F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Vienna 2016
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974294/
https://ncbi.nlm.nih.gov/pubmed/26907087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-016-2194-3
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