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Comparing Analytic Methods for Longitudinal GWAS and a Case-Study Evaluating Chemotherapy Course Length in Pediatric AML. A Report from the Children's Oncology Group

Regression analysis is commonly used in genome-wide association studies (GWAS) to test genotype-phenotype associations but restricts the phenotype to a single observation for each individual. There is an increasing need for analytic methods for longitudinally collected phenotype data. Several method...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Vujkovic, Marijana, Aplenc, Richard, Alonzo, Todd A., Gamis, Alan S., Li, Yimei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974249/
https://ncbi.nlm.nih.gov/pubmed/27547214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00139
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