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Obstructive Sleep Apnea is Associated with Low GABA and High Glutamate in the Insular Cortex

The insular cortex is injured in obstructive sleep apnea (OSA), and responds inappropriately to autonomic challenges, suggesting neural reorganization. The objective was to assess whether the neural changes result from γ-aminobutyric acid (GABA) and glutamate alterations. We studied 14 OSA patients...

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Detalhes bibliográficos
Publicado no:J Sleep Res
Main Authors: Macey, Paul M., Sarma, Manoj K., Nagarajan, Rajakumar, Aysola, Ravi, Siegel, Jerome M., Harper, Ronald M., Thomas, M. Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974152/
https://ncbi.nlm.nih.gov/pubmed/26843332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jsr.12392
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