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Targeting β1-Integrin Signaling Enhances Regeneration in Aged and Dystrophic Muscle in Mice

Interactions between stem cells and their microenvironment, or niche, are essential for stem cell maintenance and function. Our knowledge of the niche for the skeletal muscle stem cell, i.e. the satellite cell (SC), is incomplete. Here we show that β1-integrin is an essential niche molecule that mai...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Rozo, Michelle, Li, Liangji, Fan, Chen-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974124/
https://ncbi.nlm.nih.gov/pubmed/27376575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4116
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