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Highly sensitive sequencing reveals dynamic modifications and activities of small RNAs in mouse oocytes and early embryos

Small RNAs play important roles in early embryonic development. However, their expression dynamics and modifications are poorly understood because of the scarcity of RNA that is obtainable for sequencing analysis. Using an improved deep sequencing method that requires as little as 10 ng of total RNA...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Yang, Qiyuan, Lin, Jimin, Liu, Miao, Li, Ronghong, Tian, Bin, Zhang, Xue, Xu, Beiying, Liu, Mofang, Zhang, Xuan, Li, Yiping, Shi, Huijuan, Wu, Ligang
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974095/
https://ncbi.nlm.nih.gov/pubmed/27500274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1501482
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