CO(2)-evoked release of PGE2 modulates sighs and inspiration as demonstrated in brainstem organotypic culture

Inflammation-induced release of prostaglandin E(2) (PGE(2)) changes breathing patterns and the response to CO(2) levels. This may have fatal consequences in newborn babies and result in sudden infant death. To elucidate the underlying mechanisms, we present a novel breathing brainstem organotypic cu...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Forsberg, David, Horn, Zachi, Tserga, Evangelia, Smedler, Erik, Silberberg, Gilad, Shvarev, Yuri, Kaila, Kai, Uhlén, Per, Herlenius, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Computational and Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974055/
https://ncbi.nlm.nih.gov/pubmed/27377173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.14170
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