Fzd4 Haploinsufficiency Delays Retinal Revascularization in the Mouse Model of Oxygen Induced Retinopathy

Mutations in genes that code for components of the Norrin-FZD4 ligand-receptor complex cause the inherited childhood blinding disorder familial exudative vitreoretinopathy (FEVR). Statistical evidence from studies of patients at risk for the acquired disease retinopathy of prematurity (ROP) suggest...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ngo, Michael H., Borowska-Fielding, Joanna, Heathcote, Godfrey, Nejat, Sara, Kelly, Melanie E., McMaster, Christopher R., Robitaille, Johane M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973993/
https://ncbi.nlm.nih.gov/pubmed/27489958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158320
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