Biomarkers for Presymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients

Cardiotoxicity of doxorubicin (DOX) remains an important health concern. DOX cardiotoxicity is cumulative-dose-dependent and begins with the first dose of chemotherapy. No biomarker for presymptomatic detection of DOX cardiotoxicity has been validated. Our hypothesis is that peripheral blood cells (...

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Udgivet i:PLoS One
Main Authors: Todorova, Valentina K., Makhoul, Issam, Siegel, Eric R., Wei, Jeanne, Stone, Annjanette, Carter, Weleetka, Beggs, Marjorie L., Owen, Aaron, Klimberg, V. Suzanne
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973957/
https://ncbi.nlm.nih.gov/pubmed/27490685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160224
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