Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2

Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of BRCA2 (PALB2), which binds to the N-terminal region of BRCA2, is vital for its funct...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Hartford, Suzanne A., Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C., Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973925/
https://ncbi.nlm.nih.gov/pubmed/27490902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006236
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker