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Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2
Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of BRCA2 (PALB2), which binds to the N-terminal region of BRCA2, is vital for its funct...
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| Udgivet i: | PLoS Genet |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973925/ https://ncbi.nlm.nih.gov/pubmed/27490902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006236 |
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