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Mechanism of ESAT-6 membrane interaction and its roles in pathogenesis of Mycobacterium tuberculosis
The 6-kDa early secreted antigenic target (ESAT-6; EsxA) of Mycobacterium tuberculosis was first identified as a potent T-cell antigen, and it is now recognized as a pore-forming toxin that is essential for virulence of M. tuberculosis. ESAT-6 is secreted through the ESX-1 secretion system (Type VII...
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| Udgivet i: | Toxicon |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973572/ https://ncbi.nlm.nih.gov/pubmed/26456678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxicon.2015.10.003 |
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