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Characterization of differential pore-forming activities of ESAT-6 proteins from M. tuberculosis and M. smegmatis

Mycobacterium tuberculosis ESAT-6 (MtbESAT-6) plays essential roles in pathogenesis. MtbESAT-6 exhibits a unique pore-forming activity (PFA) that is not found in its ortholog from non-pathogenic Mycobacterium smegmatis (MsESAT-6). Here we characterized the differential PFAs and found that exchange o...

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Detalhes bibliográficos
Publicado no:FEBS Lett
Main Authors: Peng, Xiuli, Jiang, Guozhong, Liu, Wei, Zhang, Qi, Qian, Wei, Sun, Jianjun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973571/
https://ncbi.nlm.nih.gov/pubmed/26801203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12072
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