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Sensitivity of transformation to small differences in population density during serial passage of NIH 3T3 cells.

Early passages of the NIH 3T3 mouse cell line undergo spontaneous neoplastic transformation leading to the development of transformed foci if grown to confluence in 2% (vol/vol) calf serum (CS) and left there for more than a week. Transfer of the postconfluent cultures results in the appearance of l...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Yao, A, Rubin, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502159/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7486
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