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Structures of HSF2 Reveal Mechanisms for Differential Regulation of Human Heat Shock Factors

Heat Shock Transcription Factor (HSF) family members function in stress protection and in human disease including proteopathies, neurodegeneration and cancer. The mechanisms that drive distinct post-translational modifications, co-factor recruitment and target gene activation for specific HSF paralo...

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Bibliographic Details
Published in:Nat Struct Mol Biol
Main Authors: Jaeger, Alex M., Pemble, Charles W., Sistonen, Lea, Thiele, Dennis J.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973471/
https://ncbi.nlm.nih.gov/pubmed/26727490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3150
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