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Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

Phase I and II enzymes are involved in the metabolism of endogenous reactive compounds as well as xenobiotics, including toxicants and drugs. Genotyping studies have established several drug metabolizing enzymes as markers for risk of drug hypersensitivity. However, other candidates are emerging tha...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Sánchez-Gómez, Francisco J., Díez-Dacal, Beatriz, García-Martín, Elena, Agúndez, José A. G., Pajares, María A., Pérez-Sala, Dolores
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973429/
https://ncbi.nlm.nih.gov/pubmed/27540362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00237
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