Detoxifying Enzymes at the Cross-Roads of Inflammation, Oxidative Stress, and Drug Hypersensitivity: Role of Glutathione Transferase P1-1 and Aldose Reductase

Phase I and II enzymes are involved in the metabolism of endogenous reactive compounds as well as xenobiotics, including toxicants and drugs. Genotyping studies have established several drug metabolizing enzymes as markers for risk of drug hypersensitivity. However, other candidates are emerging tha...

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Vydáno v:Front Pharmacol
Hlavní autoři: Sánchez-Gómez, Francisco J., Díez-Dacal, Beatriz, García-Martín, Elena, Agúndez, José A. G., Pajares, María A., Pérez-Sala, Dolores
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973429/
https://ncbi.nlm.nih.gov/pubmed/27540362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00237
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