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Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury
The role of endogenous c-Kit receptor activation on cardiac cell homeostasis and repair remains largely unexplored. Transgenic mice carrying an activating point mutation (TgD814Y) in the kinase domain of the c-Kit gene were generated. c-Kit(TgD814Y) receptor was expressed in the heart during embryon...
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Pubblicato in: | Cell Death Dis |
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Autori principali: | , , , , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Nature Publishing Group
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4973348/ https://ncbi.nlm.nih.gov/pubmed/27468693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.205 |
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