Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury

The role of endogenous c-Kit receptor activation on cardiac cell homeostasis and repair remains largely unexplored. Transgenic mice carrying an activating point mutation (TgD814Y) in the kinase domain of the c-Kit gene were generated. c-Kit(TgD814Y) receptor was expressed in the heart during embryon...

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Publicado en:Cell Death Dis
Autores principales: Di Siena, S, Gimmelli, R, Nori, S L, Barbagallo, F, Campolo, F, Dolci, S, Rossi, P, Venneri, M A, Giannetta, E, Gianfrilli, D, Feigenbaum, L, Lenzi, A, Naro, F, Cianflone, E, Mancuso, T, Torella, D, Isidori, A M, Pellegrini, M
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973348/
https://ncbi.nlm.nih.gov/pubmed/27468693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.205
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