Double-edged-sword effect of IL-1β on the osteogenesis of periodontal ligament stem cells via crosstalk between the NF-κB, MAPK and BMP/Smad signaling pathways

Microenvironmental conditions can interfere with the functional role and differentiation of mesenchymal stem cells (MSCs). Recent studies suggest that an inflammatory microenvironment can significantly impact the osteogenic potential of periodontal ligament stem cells (PDLSCs), but the precise effec...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Mao, C-y, Wang, Y-g, Zhang, X, Zheng, X-y, Tang, T-t, Lu, E-y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973347/
https://ncbi.nlm.nih.gov/pubmed/27415426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.204
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