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Inflammasomes: Intracellular detection of extracellular bacteria

The non-canonical inflammasome triggers host cell death and inflammation upon recognition of cytosolic LPS. A recent report in Cell now shows that Outer Membrane Vesicles (OMVs) of extracellular Gram-negative bacteria can deliver LPS into the host cell cytosol.

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Bibliographic Details
Published in:Cell Res
Main Author: Broz, Petr
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973328/
https://ncbi.nlm.nih.gov/pubmed/27283800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.67
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