Phase 1B trial of Nab-paclitaxel plus gemcitabine, capecitabine, and cisplatin (PAXG regimen) in patients with unresectable or borderline resectable pancreatic adenocarcinoma

BACKGROUND: Nab-paclitaxel–gemcitabine combination significantly improved overall survival over gemcitabine in metastatic pancreatic adenocarcinoma. A phase 1b trial was performed (ClinicalTrials.gov number, NCT01730222) to determine the recommended phase 2 dose (RP2D) of nab-paclitaxel in combinati...

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Bibliographic Details
Published in:Br J Cancer
Main Authors: Reni, Michele, Balzano, Gianpaolo, Zanon, Silvia, Passoni, Paolo, Nicoletti, Roberto, Arcidiacono, Paolo Giorgio, Pepe, Gino, Doglioni, Claudio, Fugazza, Clara, Ceraulo, Domenica, Falconi, Massimo, Gianni, Luca
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Clinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973162/
https://ncbi.nlm.nih.gov/pubmed/27404453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.209
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