Specific KRAS amino acid substitutions and EGFR mutations predict site-specific recurrence and metastasis following non-small-cell lung cancer surgery

BACKGROUND: We aimed to evaluate whether EGFR mutations (mEGFR) and KRAS amino acid substitutions can predict first site of recurrence or metastasis after non-small-cell lung cancer (NSCLC) surgery. METHODS: Data were reviewed from 481 patients who underwent thoracic surgery for NSCLC between 2007 a...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Renaud, Stéphane, Seitlinger, Joseph, Falcoz, Pierre-Emmanuel, Schaeffer, Mickaël, Voegeli, Anne-Claire, Legrain, Michèle, Beau-Faller, Michèle, Massard, Gilbert
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973154/
https://ncbi.nlm.nih.gov/pubmed/27336603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.182
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