Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats

BACKGROUND: Pulmonary arterial hypertension (PAH) is a progressive and life-threatening disease associated with high morbidity and mortality rates. However, the exact regulatory mechanism of PAH is unknown. Although coupling factor 6 (CF6) is known to function as a repressor, its role in PAH has not...

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Veröffentlicht in:Respir Res
Hauptverfasser: Yin, Jie, You, Shuling, Li, Nannan, Jiao, Shouhai, Hu, Hesheng, Xue, Mei, Wang, Ye, Cheng, Wenjuan, Liu, Ju, Xu, Min, Yan, Suhua, Li, Xiaolu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973057/
https://ncbi.nlm.nih.gov/pubmed/27491388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0409-5
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