Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC)

In tuberous sclerosis complex (TSC), overexpression of numerous genes associated with inflammation has been observed. Among different proinflammatory cytokines, interleukin-1β (IL-1β) has been shown to be significantly involved in epileptogenesis and maintenance of seizures. Recent evidence indicate...

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Veröffentlicht in:J Mol Neurosci
Hauptverfasser: Fuso, A., Iyer, A. M., van Scheppingen, J., Maccarrone, M., Scholl, T., Hainfellner, J. A., Feucht, M., Jansen, F. E., Spliet, W. G., Krsek, P., Zamecnik, J., Mühlebner, A., Aronica, E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer US 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972849/
https://ncbi.nlm.nih.gov/pubmed/27122151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-016-0750-7
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