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Bimodal expression of PHO84 is modulated by early termination of antisense transcription
Many S. cerevisiae genes encode antisense transcripts some of which are unstable and degraded by the exosome component Rrp6. Loss of Rrp6 results in the accumulation of long PHO84 antisense RNAs and repression of sense transcription through PHO84 promoter deacetylation. We used single molecule resol...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972572/ https://ncbi.nlm.nih.gov/pubmed/23770821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2598 |
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