Donor-specific antibodies require preactivated immune system to harm renal transplant

BACKGROUND: It is an unresolved issue why some kidney transplant recipients with pretransplant donor-specific HLA antibodies (DSA) show a high transplant failure rate, whereas in other patients DSA do not harm the graft. We investigated whether help from preactivated T-cells might be necessary for D...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Süsal, Caner, Döhler, Bernd, Ruhenstroth, Andrea, Morath, Christian, Slavcev, Antonij, Fehr, Thomas, Wagner, Eric, Krüger, Bernd, Rees, Margaret, Balen, Sanja, Živčić-Ćosić, Stela, Norman, Douglas J., Kuypers, Dirk, Emonds, Marie-Paule, Pisarski, Przemyslaw, Bösmüller, Claudia, Weimer, Rolf, Mytilineos, Joannis, Scherer, Sabine, Tran, Thuong H., Gombos, Petra, Schemmer, Peter, Zeier, Martin, Opelz, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972543/
https://ncbi.nlm.nih.gov/pubmed/27333031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.06.006
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