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Enhancing radiotherapy through a greater understanding of homologous recombination

Radiotherapy for the treatment of cancer can cause a wide range of cellular effects, the most biologically potent of which is the double strand break in DNA. The process of repairing DNA double strand breaks involves one of two major mechanisms: non-homologous end-joining or homologous recombination...

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Detalhes bibliográficos
Publicado no:Semin Radiat Oncol
Main Authors: Barker, Christopher A., Powell, Simon N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972489/
https://ncbi.nlm.nih.gov/pubmed/20832019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2010.05.001
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