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Structure of the Escherichia coli ArnA N‐formyltransferase domain in complex with N (5)‐formyltetrahydrofolate and UDP‐Ara4N

ArnA from Escherichia coli is a key enzyme involved in the formation of 4‐amino‐4‐deoxy‐l‐arabinose. The addition of this sugar to the lipid A moiety of the lipopolysaccharide of pathogenic Gram‐negative bacteria allows these organisms to evade the cationic antimicrobial peptides of the host immune...

詳細記述

保存先:
書誌詳細
出版年:Protein Sci
主要な著者: Genthe, Nicholas A., Thoden, James B., Holden, Hazel M.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972212/
https://ncbi.nlm.nih.gov/pubmed/27171345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2938
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