A simple DNA handle attachment method for single molecule mechanical manipulation experiments

Manipulating single molecules and systems of molecules with mechanical force is a powerful technique to examine their physical properties. Applying force requires attachment of the target molecule to larger objects using some sort of molecular tether, such as a strand of DNA. DNA handle attachment o...

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Bibliographic Details
Published in:Protein Sci
Main Authors: Min, Duyoung, Arbing, Mark A., Jefferson, Robert E., Bowie, James U.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Methods and Applications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972209/
https://ncbi.nlm.nih.gov/pubmed/27222403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2952
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