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Effect of circular permutations on transient partial unfolding in proteins

Under native conditions, proteins can undergo transient partial unfolding, which may cause proteins to misfold or aggregate. A change in sequence connectivity by circular permutation may affect the energetics of transient partial unfolding in proteins without altering the three‐dimensional structure...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Chen, Chen, Yun, Jung‐Hun, Kim, Jae‐Hoon, Park, Chiwook
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972204/
https://ncbi.nlm.nih.gov/pubmed/27164316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2945
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