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Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.

Tissue-type plasminogen activator and urokinase are serine proteases secreted by many cell types that participate in biological processes, such as tissue restructuring, cell migration, and tumor metastasis. Clinically, these proteases are used to dissolve coronary fibrin clots that are the proximal...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Orth, K, Madison, E L, Gething, M J, Sambrook, J F, Herz, J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502153/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7422
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