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Impact of perampanel on pharmacokinetics of concomitant antiepileptics in patients with partial‐onset seizures: pooled analysis of clinical trials

AIMS: To evaluate the impact of perampanel and demographics on clearance of concomitant antiepileptic drugs (AEDs), in patients with refractory partial‐onset seizures. METHODS: Pooled data from three Phase III clinical studies with adjunctive perampanel were used. Blood samples for evaluation of 11...

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Publicado en:Br J Clin Pharmacol
Autores principales: Majid, Oneeb, Laurenza, Antonio, Ferry, Jim, Hussein, Ziad
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972158/
https://ncbi.nlm.nih.gov/pubmed/27038098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12951
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