CPAP promotes timely cilium disassembly to maintain neural progenitor pool

A mutation in the centrosomal‐P4.1‐associated protein (CPAP) causes Seckel syndrome with microcephaly, which is suggested to arise from a decline in neural progenitor cells (NPCs) during development. However, mechanisms of NPCs maintenance remain unclear. Here, we report an unexpected role for the c...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Gabriel, Elke, Wason, Arpit, Ramani, Anand, Gooi, Li Ming, Keller, Patrick, Pozniakovsky, Andrei, Poser, Ina, Noack, Florian, Telugu, Narasimha Swamy, Calegari, Federico, Šarić, Tomo, Hescheler, Jürgen, Hyman, Anthony A, Gottardo, Marco, Callaini, Giuliano, Alkuraya, Fowzan Sami, Gopalakrishnan, Jay
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972140/
https://ncbi.nlm.nih.gov/pubmed/26929011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593679
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