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The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6

Follicular T helper (Tfh) cells are key regulators of the germinal center reaction and long‐term humoral immunity. Tfh cell differentiation requires the sustained expression of the transcriptional repressor Bcl6; however, its regulation in CD4(+) T cells is incompletely understood. Here, we report t...

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Vydáno v:EMBO J
Hlavní autoři: Stauss, Dennis, Brunner, Cornelia, Berberich‐Siebelt, Friederike, Höpken, Uta E, Lipp, Martin, Müller, Gerd
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972135/
https://ncbi.nlm.nih.gov/pubmed/26957522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591459
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